{"id":22711,"date":"2020-07-28T10:00:46","date_gmt":"2020-07-28T07:00:46","guid":{"rendered":"https:\/\/www.silutesnaujienos.lt\/lt\/?p=22711"},"modified":"2020-07-28T09:26:21","modified_gmt":"2020-07-28T06:26:21","slug":"naturalus-papildas-pagyvenusiems-zmonems-gali-puikiai-papildyti-cholesterolio-kieki-mazinanciu-vaistu-poveiki","status":"publish","type":"post","link":"https:\/\/www.silutesnaujienos.lt\/lt\/naturalus-papildas-pagyvenusiems-zmonems-gali-puikiai-papildyti-cholesterolio-kieki-mazinanciu-vaistu-poveiki\/","title":{"rendered":"Nat\u016bralus papildas pagyvenusiems \u017emon\u0117ms gali puikiai papildyti cholesterolio kiek\u012f ma\u017einan\u010di\u0173 vaist\u0173 poveik\u012f"},"content":{"rendered":"

Nepaisant to, kad statinai jau daugyb\u0119 de\u0161imtme\u010di\u0173 veiksmingai ma\u017eina potencialiai kenksming\u0105 cholesterolio kiek\u012f kraujyje, \u0161ios pla\u010diai i\u0161ra\u0161in\u0117jamos grup\u0117s sintetiniai vaistai turi ir tamsi\u0105j\u0105 pus\u0119. Statinai gali sukelti nepageidaujam\u0173 rei\u0161kini\u0173 raumenims; kai kuriais atvejais \u0161ie rei\u0161kiniai b\u016bna tokie stipr\u016bs, kad priver\u010dia \u017emones nustoti vartoti jiems i\u0161ra\u0161ytus cholesterolio kiek\u012f kraujyje ma\u017einan\u010dius vaistus.<\/strong><\/p>\n

\u012edomu tai, kad, remiantis naujosios gegu\u017e\u0117s m\u0117nes\u012f \u201eJournal of the American Heart Association\u201c \u017eurnale paskelbtos atsitiktini\u0173 im\u010di\u0173 kontroliuojam\u0173 tyrim\u0173 meta analiz\u0117s1 duomenimis, lygiagre\u010diai vartojant populiaraus energijos suteikian\u010dio \u012f vitamin\u0105 pana\u0161aus junginio kofermento Q10 papildus, nepageidaujamus simptomus galima su\u0161velninti. Anot naujosios ap\u017evalgos apimt\u0173 mokslinink\u0173, kofermento Q10 papildai ilgainiui gali tapti visuotinai rekomenduojamais papildais statin\u0173 sukeliamiems nepageidaujamiems raumen\u0173 rei\u0161kiniams su\u0161velninti.<\/strong><\/p>\n

Suma\u017e\u0117ja raumen\u0173 skausmai, nuovargis ir silpnumas<\/strong><\/p>\n

Atlikdami meta analiz\u0119, mokslininkai i\u0161studijavo 12 atsitiktini\u0173 im\u010di\u0173 kofermento Q10 poveikio statinais gydomiems tiriamiesiems tyrim\u0173 i\u0161vadas. 294 tiriamieji greta \u012fprast\u0173 statin\u0173 buvo paskirta vartoti kofermento Q10, o 281 tiriamajam \u2013 atitinkama placebo doz\u0117. Lygindami tyrim\u0173 i\u0161vadas, mokslininkai pasteb\u0117jo, kad kofermento Q10 ir statin\u0173 derinys palengvino \u012fvairius nepageidaujamus simptomus, pavyzd\u017eiui, raumen\u0173 skausm\u0105, silpnum\u0105, spazmus ir nuovarg\u012f, kurie paprastai siejami su gydymu statinais. Min\u0117t\u0173 tyrim\u0173 atvejais buvo skiriama 100-600 mg kofermento Q10 dienos doz\u0117.
\n\"\"<\/a>
\nPadeda raumen\u0173 l\u0105stel\u0117ms gaminti energij\u0105<\/strong><\/p>\n

Sprend\u017eiant esmin\u0117s nepageidaujam\u0173 statin\u0173 sukeliam\u0173 rei\u0161kini\u0173 raumenims ir kofermento Q10 poveikio prie\u017easties klausim\u0105 buvo aptariami \u012fvair\u016bs galimi poveikio mechanizmai. Vienas i\u0161 j\u0173 yra mitochondrij\u0173 disfunkcija vadinamas rei\u0161kinys, pasirei\u0161kiantis, kai raumen\u0173 l\u0105steli\u0173 \u201ej\u0117gain\u0117s\u201c mitochondrijos nustoja gaminti tinkamai raumen\u0173 veiklai u\u017etikrinti b\u016btin\u0105 energij\u0105. Mokslininkai pasteb\u0117jo, kad, nuolat vartojant statinus, kofermento Q10 kiekis \u0161irdies ir skeleto raumenyse suma\u017e\u0117jo 16-54 %. \u0160is kofermentas yra nepakei\u010diamas mitochondrij\u0173 apykaitos elementas, tad statin\u0173 sukeliamu jo suma\u017e\u0117jimu b\u016bt\u0173 galima paai\u0161kinti energijos apykaitos ir paskesn\u012f raumen\u0173 l\u0105steli\u0173 veiklos sutrikim\u0105.<\/p>\n

Gyvybi\u0161kai svarbus \u0161ird\u017eiai junginys<\/strong><\/p>\n

Kofermento Q10 poveikis \u0161irdies raumens veiklai pla\u010diai aptartas keleto tyrim\u0173 i\u0161vadose. 2014 m. \u201eJAAC Heart Failure\u201c \u017eurnale paskelbto \u201eQ-Symbio\u201c tyrimo metu i\u0161 viso 420 l\u0117tiniu \u0161irdies nepakankamumu sergantiems tiriamiesiems greta \u012fprast\u0173 vaist\u0173 \u0161ird\u017eiai buvo skiriama 300 mg kofermento Q10 per dien\u0105 arba atitinkama placebo doz\u0117. Vartojusi\u0173j\u0173 koferment\u0105 Q10 grup\u0117je rizika numirti d\u0117l \u0161irdies ligos buvo 43 % ma\u017eesn\u0117, be to, papildas \u017eenkliai pagerino \u0161i\u0173 tiriam\u0173j\u0173 \u0161irdies veikl\u0105.<\/p>\n

Kitas tyrimas, \u201eKiSel-10\u201c, buvo atliktas su 443 sveikais pagyvenusiais tiriamaisiais. Pusei j\u0173 buvo paskirta vartoti 200 miligram\u0173 kofermento Q10 ir 200 mikrogram\u0173 nat\u016brali\u0173 seleno mieli\u0173, o kitai pusei – placebo. Remiantis \u0161io 2013 m. \u201eInternational Journal of Cardiology\u201c \u017eurnale paskelbto tyrimo i\u0161vadomis, koferment\u0105 Q10 ir selen\u0105 vartojusi\u0173 tiriam\u0173j\u0173 grup\u0117je pasitaik\u0117 54 % ma\u017eiau mir\u010di\u0173 d\u0117l \u0161irdies ir kraujagysli\u0173 lig\u0173 ir \u017eenkliai pager\u0117jo \u0161i\u0173 tiriam\u0173j\u0173 \u0161irdies raumens veikla.<\/p>\n

Papildas naudingas visiems pagyvenusiems \u017emon\u0117ms<\/strong><\/p>\n

Apibendrinant galima teigti, kad kofermentas Q10 vaidina svarb\u0173 vaidmen\u012f apskritai vis\u0173 raumen\u0173 ir atskirai \u0161irdies raumens sveikatai. Gydymo statinais sukeliamas kofermento Q10 kiekio suma\u017e\u0117jimas sustiprina kiekvienam \u017emogui b\u016bdingo nat\u016bralaus, am\u017eiaus nulemto kofermento Q10 kiekio ma\u017e\u0117jimo pasekmes. D\u0117l to tik padid\u0117ja pavojus mitochondrij\u0173 veiklai ypatingai daug energijos reikaling\u0173 tip\u0173 l\u0105stel\u0117se, pavyzd\u017eiui, raumen\u0173 l\u0105stel\u0117se. D\u0117l \u0161ios prie\u017easties vartoti kofermento Q10 papildus, ko gero, yra i\u0161mintingas sprendimas visiems pagyvenusiems \u017emon\u0117ms apskritai, kadangi taip galima pad\u0117ti palaikyti normali\u0105 raumen\u0173 l\u0105steli\u0173 energijos apykait\u0105. Vartojan\u010di\u0173 statinus atveju min\u0117ti papildai gali b\u016bti ypa\u010d naudingi kaip priemon\u0117 statin\u0173 sukeliamam gyvybi\u0161kai svarbaus kofermento Q10 kiekio ma\u017e\u0117jimui kompensuoti.<\/p>\n

\u0160altiniai:
\n1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
\nJournal of the American Heart Association, DOI:10.1161\/JAHA.118.009835.
\n2. The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure: Results From Q-SYMBIO: A Randomized Double-Blind Trial.
\nJACC Heart Fail 2014 Dec;2(6):641-9.
\n3. Cardiovascular Mortality and N-terminal-proBNP Reduced After Combined Selenium and Coenzyme Q10 Supplementation: A 5-year Prospective Randomized Double-Blind Placebo-Controlled Trial Among Elderly Swedish Citizens.
\nInt J Cardiol 2013 Sep 1;167(5):1860-6.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nepaisant to, kad statinai jau daugyb\u0119 de\u0161imtme\u010di\u0173 veiksmingai ma\u017eina potencialiai kenksming\u0105 cholesterolio kiek\u012f kraujyje, \u0161ios pla\u010diai i\u0161ra\u0161in\u0117jamos grup\u0117s sintetiniai vaistai turi ir tamsi\u0105j\u0105 pus\u0119. Statinai gali sukelti nepageidaujam\u0173 rei\u0161kini\u0173 raumenims; kai kuriais atvejais \u0161ie rei\u0161kiniai b\u016bna tokie stipr\u016bs, kad priver\u010dia \u017emones nustoti vartoti jiems i\u0161ra\u0161ytus cholesterolio kiek\u012f kraujyje ma\u017einan\u010dius vaistus. \u012edomu tai, kad, remiantis naujosios […]<\/p>\n","protected":false},"author":2,"featured_media":22712,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[104,47],"class_list":["post-22711","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sveikatos-saltinis","tag-papildai","tag-pirmasis"],"yoast_head":"\nNat\u016bralus papildas pagyvenusiems \u017emon\u0117ms gali puikiai papildyti cholesterolio kiek\u012f ma\u017einan\u010di\u0173 vaist\u0173 poveik\u012f - \u0160ilut\u0117s naujienos<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.silutesnaujienos.lt\/lt\/naturalus-papildas-pagyvenusiems-zmonems-gali-puikiai-papildyti-cholesterolio-kieki-mazinanciu-vaistu-poveiki\/\" \/>\n<meta property=\"og:locale\" content=\"lt_LT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nat\u016bralus papildas pagyvenusiems \u017emon\u0117ms gali puikiai papildyti cholesterolio kiek\u012f ma\u017einan\u010di\u0173 vaist\u0173 poveik\u012f - \u0160ilut\u0117s naujienos\" \/>\n<meta property=\"og:description\" content=\"Nepaisant to, kad statinai jau daugyb\u0119 de\u0161imtme\u010di\u0173 veiksmingai ma\u017eina potencialiai kenksming\u0105 cholesterolio kiek\u012f kraujyje, \u0161ios pla\u010diai i\u0161ra\u0161in\u0117jamos grup\u0117s sintetiniai vaistai turi ir tamsi\u0105j\u0105 pus\u0119. 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