{"id":61755,"date":"2024-06-05T08:06:53","date_gmt":"2024-06-05T05:06:53","guid":{"rendered":"https:\/\/www.silutesnaujienos.lt\/lt\/?p=61755"},"modified":"2024-06-05T08:13:37","modified_gmt":"2024-06-05T05:13:37","slug":"kolagenas-svarbi-medziaga-zmogaus-organizmui-ka-apie-ji-reiketu-zinoti","status":"publish","type":"post","link":"https:\/\/www.silutesnaujienos.lt\/lt\/kolagenas-svarbi-medziaga-zmogaus-organizmui-ka-apie-ji-reiketu-zinoti\/","title":{"rendered":"Kolagenas \u2013 svarbi med\u017eiaga \u017emogaus organizmui. K\u0105 apie j\u012f reik\u0117t\u0173 \u017einoti?"},"content":{"rendered":"

Kas yra kolagenas?<\/strong><\/p>\n

Kolagenas \u2013 tai pagrindinis jungiamojo audinio baltymas. Jo yra visose organizmo sistemos dalyse: plaukuose, odoje, rai\u0161\u010diuose, sausgysl\u0117se, raumenyse, kraujagysl\u0117se, kauluose. Baltymai sudaro iki 40 proc. jungiamojo audinio. I\u0161 j\u0173 vienas svarbiausi\u0173 yra kolagenas, sudarantis did\u017ei\u0105j\u0105 baltym\u0173 dal\u012f. Daug kolageno yra s\u0105nari\u0173 kremzl\u0117se: \u010dia \u0161is baltymas palaiko audini\u0173 elastingum\u0105 bei ma\u017eina j\u0173 nusid\u0117v\u0117jimo rizik\u0105.<\/p>\n

Kokia yra kolageno reik\u0161m\u0117 jungiamajam audiniui?<\/strong><\/p>\n

Su am\u017eiumi, vyraujant degeneraciniams procesams, jungiamasis audinys tampa vis labiau pa\u017eeid\u017eiamas. Kremzl\u0117s ima dilti, gali b\u016bti pa\u017eeid\u017eiamas ir kaulinis audinys, raumenynas silpsta, oda suglemba, pasikei\u010dia plauk\u0173, nag\u0173 strukt\u016bra. Opi tampa \u017emogaus i\u0161vaizdos, gro\u017eio problema, kuri stipriai siejasi su kolageno stoka organizme.<\/p>\n

Tr\u016bkstant kolageno gali vystytis senatvin\u0117 toliaregyst\u0117, \u0161irdies bei kraujagysli\u0173 ligos. Sergant \u0161irdies ir kraujagysli\u0173 ligomis svarbu i\u0161saugoti elastingas kraujagysles, nes jos kiet\u0117ja, o kietesn\u0117s kraujagysl\u0117s grei\u010diau \u012ftr\u016bksta. Taip susidaro nat\u016bralios s\u0105lygos vystytis aterosklerozei, kuri yra jungiamojo audinio irimo ir kolageno ma\u017e\u0117jimo kraujagysl\u0117se pasekm\u0117.<\/p>\n

Kokia yra kolageno tip\u0173 \u012fvairov\u0117? Koks j\u0173 vaidmuo jungiamajam audiniui?<\/strong><\/p>\n

Kolageno tip\u0173 yra daug, tod\u0117l pamin\u0117siu pagrindinius, kurie dominuoja audiniuose. Kremzl\u0117s u\u017epildo sud\u0117tyje vyrauja II tipo kolagenas<\/em><\/strong>, kauliniame audinyje \u2013 I tipo<\/em><\/strong>, raumenyne \u2013 I ir III tipo<\/em><\/strong>, odoje \u2013 III tipo<\/em><\/strong> kolagenas. Kolagenas gali b\u016bti skirtingos molekulin\u0117s mas\u0117s. Priklausomai nuo hidroliz\u0117s laipsnio i\u0161skiriamos trys pagrindin\u0117s kolagen\u0173 derivat\u0173 grup\u0117s:<\/p>\n

    \n
  1. Nedenat\u016bruotas (nat\u016bralus) arba natyvinis kolagenas<\/em><\/strong>. Jo molekulin\u0117 mas\u0117 yra apie 300 kilodalton\u0173 (kDa) ir jis vadinamas pa\u010diu aktyviausiu.<\/li>\n
  2. \u017delatina<\/em><\/strong> (molekulin\u0117 mas\u0117 nuo 20\u201390 kDa).<\/li>\n
  3. Hidrolizuotas kolagenas<\/em><\/strong>, kurio molekulin\u0117 mas\u0117 2\u20139 kDa (smulkiausios strukt\u016bros baltymas).<\/li>\n<\/ol>\n

    Nustatyta, kad sergant reumatoidiniu artritu II tipo natyvinis<\/strong>, nedenat\u016bruotas kolagenas atlieka tarsi treniruot\u0117s vaidmen\u012f. Jis veikia plonajame \u017earnyne didindamas tolerancij\u0105 ir slopindamas u\u017edegim\u0105, kur\u012f sukelia imunin\u0117s sistemos imunokompetentin\u0117s l\u0105stel\u0117s. Da\u017eniausiai u\u017etenka nedideli\u0173 natyvinio kolageno dozi\u0173 siekiant apraminti imuniteto atsak\u0105.<\/p>\n

    \u017delatina asocijuojasi su gyvulini\u0173 subprodukt\u0173 patiekalu \u2013 \u0161altiena, kurios pagrindas yra drebu\u010diai. Jei \u017emogus tok\u012f maist\u0105 gali valgyti, \u2013 kod\u0117l gi ne. Bet da\u017enai \u0161altienos nepatariama valgyti d\u0117l am\u017eiaus, galim\u0173 gretutini\u0173 lig\u0173 (pavyzd\u017eiui, \u0161irdies ir kraujagysli\u0173), ateroskleroz\u0117s i\u0161sivystymo gr\u0117sm\u0117s. Visa tai reikia \u012fvertinti.<\/p>\n

    Hidroliz\u0117 didina kolageno funkcines savybes, jo biologin\u012f prieinamum\u0105. Hidrolizuotas kolagenas d\u0117l itin ma\u017eo molekulinio svorio yra puikiai vir\u0161kinamas, lengvai pasisavinamas, gerai pasiskirsto organizme, o tikimyb\u0117, kad jis sukels alergij\u0105, yra ma\u017ea. Hidrolizuotas kolagenas gerai absorbuojamas \u017earnyne, patenka \u012f kraujotak\u0105 ir \u012f tikslines vietas, kuriose \u0161ios med\u017eiagos tr\u016bksta. Taigi, per tam tikr\u0105 laik\u0105 kremzl\u0117 pasipildo reikiamu hidrolizuoto kolageno kiekiu, aktyvinamas kremzl\u0117s pagrindini\u0173 l\u0105steli\u0173 \u2013 chondrocit\u0173 gyvybingumas. Chondrocitai gamina visavert\u0119 kremzl\u0117s matric\u0105, u\u017epild\u0105, ir taip renovuojamas kremzl\u0117s audinys.<\/p>\n

    Kod\u0117l visavertei kolageno sintezei svarbios papildomos sinergin\u0117s med\u017eiagos?<\/strong><\/p>\n

    Siekiant suma\u017einti u\u017edegimin\u012f proces\u0105 ir sustiprinti tolerancij\u0105 kolagenui, preparat\u0173 sud\u0117tis papildoma antioksidantais. Svarbi sinergin\u0117 med\u017eiaga yra askorbo r\u016bg\u0161tis (vitaminas C). Tr\u016bkstant vitamino C<\/em><\/strong> formuojasi nevisavertis kolagenas \u2013 kolageno strukt\u016bra praranda stabilum\u0105.<\/p>\n

    Taip pat svarbus vitaminas E<\/em><\/strong>, kuris slopina u\u017edegim\u0105. Reikalinga ir aminor\u016bg\u0161tis L\u00adleucinas<\/em><\/strong>, reguliuojantis baltym\u0173 sintez\u0119. Be to, \u0161i aminor\u016bg\u0161tis dalyvauja lipid\u0173 ir angliavandeni\u0173 metabolizme. Prie sinergini\u0173 med\u017eiag\u0173 taip pat priskiriamas proteolitinis augalin\u0117s kilm\u0117s fermentas bromelainas<\/em><\/strong>. Jis i\u0161skiriamas i\u0161 ananas\u0173 vaisi\u0173 arba \u017eiev\u0117s ir pasi\u017eymi u\u017edegim\u0105 slopinan\u010diu poveikiu. Bromelainas tarsi suvir\u0161kina suirusius arba pakitusios strukt\u016bros baltymus. Juk, kad atsinaujint\u0173 kremzl\u0117s audinys, pirmiausia reikia pa\u0161alinti \u012fvairias metabolines atliekas, atplai\u0161as \u2013 paruo\u0161ti s\u0105lygas naujai audini\u0173 statybai.<\/p>\n

    K\u0105 svarbu \u012fvertinti renkantis kolageno preparatus?<\/strong><\/p>\n

    Labai svarbu pabr\u0117\u017eti technologijos kokyb\u0119, preparato kompozicij\u0105, sinergij\u0105 su skirtingomis med\u017eiagomis ir proporcijas tarp natyvinio (nat\u016bralaus) kolageno bei hidrolizuoto kolageno. Taip pat svarbu, kad patentuot\u0173 preparat\u0173 patikimumas b\u016bt\u0173 paremtas klinikiniais tyrimais. \u012e patikim\u0173 preparat\u0173 sud\u0117t\u012f \u012feina klini\u0161kai testuoti patentuoti kolagenai. Tai \u2013 vadinamieji specifiniai bioaktyv\u016bs kolageno peptidai.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Kas yra kolagenas? Kolagenas \u2013 tai pagrindinis jungiamojo audinio baltymas. Jo yra visose organizmo sistemos dalyse: plaukuose, odoje, rai\u0161\u010diuose, sausgysl\u0117se, raumenyse, kraujagysl\u0117se, kauluose. Baltymai sudaro iki 40 proc. jungiamojo audinio. I\u0161 j\u0173 vienas svarbiausi\u0173 yra kolagenas, sudarantis did\u017ei\u0105j\u0105 baltym\u0173 dal\u012f. Daug kolageno yra s\u0105nari\u0173 kremzl\u0117se: \u010dia \u0161is baltymas palaiko audini\u0173 elastingum\u0105 bei ma\u017eina j\u0173 nusid\u0117v\u0117jimo […]<\/p>\n","protected":false},"author":2,"featured_media":61759,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53],"tags":[47],"class_list":["post-61755","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sveikatos-saltinis","tag-pirmasis"],"yoast_head":"\nKolagenas \u2013 svarbi med\u017eiaga \u017emogaus organizmui. 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